butabarbital will lower the level or result of doravirine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated.butabarbital will lessen the extent or result of midazolam by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.Teniposide: Barbiturates may perhaps lessen the serum concentration of Teniposide.